Introduction
Biosprint® contains live yeast of Saccharomyces cerevisiae MUCL 39885. The product is approved for use in the EU in piglets, sows, dairy cows, horses, cattle for fattening, minor ruminants for fattening and minor ruminants for dairy production.
Manufacturer´s main claims
Protects the gut wall
Produces beneficial metabolites
Improves digestion of nutrients
Improves feed conversion
Weaned litter weight increases
Technical specifications of Biosprint
EU category
Zootechnical additive
Functional group of additives
Gut flora stabiliser
Active substance
Saccharomyces cerevisiae (MUCL 39885)
Activity in the product
1010 CFU/g product
EU approval
No maximum content of the additive for any of the animal categories below.
Piglets: 3 x 109 CFU/kg feed
Sows: 6.4 x 109 CFU/kg feed
Dairy cows: 2 x 109 CFU/kg feed
Horses: 3 x 109 CFU/kg feed
Cattle for fattening: 4 x 109 CFU/kg feed
Minor ruminants for fattening: 4 x 109 CFU/kg feed
Minor ruminants for dairy production: 2 x 109 CFU/kg feed
All Suidae other than for reproduction purposes and weaned piglets: 3 x 109 CFU/kg feed
All Suidae for reproduction purposes other than sows: 6.4 x 109 CFU/kg feed
Dogs: 7 x 1010 CFU/kg feed
End of period of authorisation
Piglets: 13 April 2031
Sows: 16 August 2030
Dairy cows: 16 August 2030
Horses: 16 August 2030
Cattle for fattening: 19 November 2023*
Minor ruminants for fattening and minor ruminants for dairy production: 17 February 2026
All Suidae other than for reproduction purposes and weaned piglets: 16 March 2032
All Suidae for reproduction purposes other than sows: 16 March 2032
Dogs: 16 March 2032
*: Following the provisions of Art. 14 of Reg. (EC) No 1831/2003, an application, in accordance with Article 7, has been submitted
EU code
4b1710
Recommended dosage
Cattle for fattening: minimum recommended dosage is 3.6 x 1010 CFU/head/day
Piglets: 0.3 kg/t feed
Sows: 0.64 kg/t feed
Product storage stability
The product's stability was tested over 24 months, where the product was stored in an aluminium foil package under a vacuum. EFSA states that shelf life was demonstrated. However, no data are presented.
Storage stability in feed and premix
Biosprint was added to a vitamin/mineral premix and stored for nine months at 25°C/60% relative humidity or 40°C/75% relative humidity. At 25°C, there was a loss of 0.5 log units at four months of storage. The product rapidly lost activity when stored at 40°C.
Heat stability
The manufacturer claims that the product is heat stable at pelleting temperatures up to 80°C
Carrier
Pure yeast product. Without carrier
Package size
15 kg bags
Handling
The product should be considered as a potential skin and eye irritant and sensitiser.
Producer
Prosol SpA
List of references
EFSA (2010). Scientific Opinion on the Safety and Efficacy of Biosprint (Saccharomyces cerevisiae) as a feed additive for horses. EFSA Journal 2010; 8(7):1659
EFSA (2011). Scientific Opinion on the Safety and Efficacy of Biosprint (Saccharomyces cerevisiae) for cattle for fattening. EFSA Journal 2011; 9(11):2439
EU (2013). Commission Regulation (EU) No 1059/2013 of 29 October 2013 concerning the authorisation of a preparation of Saccharomyces cerevisiae MUCL 39885 as a feed additive for cattle for fattening and amending Regulation (EC) No 492/2006 (holder of the authorisation Prosol SpA). Official Journal of the European Union L 289/30-32
EU (2016). Commission Regulation (EU) No 2016/104 of 27 January 2016 concerning the authorisation of a preparation of Saccharomyces cerevisiae MUCL 39885 as a feed additive for minor ruminants for fattening and minor ruminants for dairy production (holder of the authorisation Prosol SpA). Offiicial Journal of the European Union. L 21/71-73
EU (2020). Commission Implementing Regulation (EU) No 2020/1096 of 24 July concerning the renewal of the authorisation of Saccharomyces cerevisiae MUCL 39885 as a feed additive for dairy cows and horses and repealing Regulation (EU) No 1119/2010 (holder of authorisation Prosol S.p.A.). Official Journal of the European Union. L241/20-22
EU (2020). Commission Implementing Regulation (EU) No 2020/1094 of 24 July concerning the renewal of the authorisation of Saccharomyces cerevisiae MUCL 39885 as a feed additive for sows and repealing Regulation (EC) No 896/2009 (holder of authorisation Prosol S.p.A.). Official Journal of the European Union. L241/15-17
EU (2021). Commission Implementing Regulation (EU) No 2021/508 of 23 March 2021 concerning the renewal of the authorisation of a preparation of Saccharomyces cerevisiae MUCL 39885 as a feed additive for weaned piglets and repealing Regulation (EU) No 170/2011 (holder of authorisation Prosol S.p.A.). Official Journal of the European Union. L 102/11
EU (2022). COMMISSION IMPLEMENTING REGULATION (EU) 2022/272 of 23 February 2022 concerning the authorisation of a preparation of Saccharomyces cerevisiae MUCL 39885 as a feed additive for all suidae other than weaned piglets and sows, and dogs (holder of authorisation: Prosol S.p.A.). Official Journal of the European Union. L43/14-16