Introduction
Econase® XT contains beta-xylanase. The product is authorised for use in the EU in piglets and pigs for fattening. In addition, it is also authorised for all major avian species.
Econase® XT is available in dry and liquid forms.
Manufacturer´s main claims
Optimises feed efficiency
Reduces feed costs
Stable at very high pelleting temperatures
Technical specifications of Econase® (Solid and Liquid)
EU category
Zootechnical additives
Functional group of additives
Digestibility enhancers
Active substance
endo-1,4-beta-xylanase (EC 3.2.1.8)
Enzymatic activity in the product
160,000 BXU/g product
EU approval, minimum content
Piglets: 24,000 BXU/kg feed
Chickens for fattening: 8,000 BXU/kg feed
Chickens reared for laying: 8,000 BXU/kg feed
Turkeys for fattening: 16,000 BXU/kg feed
Turkeys reared for breeding: 16,000 BXU/kg feed
End of period of EU authorisation
20 July 2033
Piglets (weaned)
Chickens for fattening
Chickens reared for laying
Turkeys for fattening
Turkeys reared for breeding
EU code
4a8i
Production organism
Trichoderma reseei (CBS 114044)
Product storage stability
Three batches of each dry formulation were stored in sealed plastic bags for 24 months at 25 or 30°C, and further samples were stored at 40°C.
After 24 months of storage, the remaining enzyme activity ranged from 94 to 100% at 25°C for the XT 25 and XT 5P products. For the XT P product, 84-89% of the enzyme activity was left. At 30°C, the remaining enzymatic activity ranged from 71 to 85% (XT), 83 to 86% (XT 5P) and above 73% (XT P). After 9 months at 40°C, 83-91% (XT), 87-96% (XT 5P) and 75-81% (XT P) remained.
Three batches of the liquid formulation were stored in closed bottles for 24 months at 6, 25 or 30°C. Further samples were stored at 40°C for 12 months. After 24 months of storage, the remaining enzyme activity ranged from 95 to 100% at 25°C. At 30°C, the remaining enzymatic activity ranged from 86 to 100%. At 40°C, 67-99% of the initial enzymatic activity was recovered in the XT 25L formulation. In the XT L formulation, 95-100% of the initial enzymatic activity remained.
Storage stability in premix and feed
Three different batches of the solid formulation were supplemented to a vitamin/mineral premix without choline chloride. Samples of the premix were stored for six months at room temperature. After six months of storage, the remaining enzyme activity ranged from 80-83% with XT 25, 95-100% with XT 5 P and 86-88% with XT P.
Three batches of the XT 25 formulation were also added to a vitamin/mineral premix with choline chloride and stored the same way as the premixes without choline chloride. After six months of storage, the remaining enzyme activity ranged from 82 to 98%.
The stability of the liquid xylanase when sprayed onto pelleted feed was also tested. After three months of storage at room temperature, the residual activity ranged from 93% to 100%.
The stability of the solid products was tested in mash and pelleted feed. Pelleting took place at 80°C. After six months of storage, 100% of the xylanase (XT 5 P) activity remained in both mash and pelleted feed. For the XT P formulation, 96 to 100% activity was left.
Heat stability
The solid products were tested at various temperatures: 70, 75, 80, 85, 90 and 95°C. Below are the results for the lowest and highest temperatures.
Remaining activity XT 25:
70°C: 93-99%
95°C: 77-89%
Remaining activity XT 5 P:
70°C: 96-100%
95°C: 87-89%
Remaining activity XT P:
70°C: 99-100%
95°C: 88-92%
Homogeneity
Both product forms were tested for their homogeneous mixing ability in the feed. Twenty subsamples of each mash and pelleted feed supplemented with the product were analysed. The liquid form was sprayed onto pellets.
Coefficient of variance:
XT 25: 6% (meal), 5% (pellets)
XT 5 P: 7% (meal), 6% (pellets)
XT TP: 8% (meal), 10% (pellets)
Physical properties
A dusting potential test showed the solid formulation (XT P) has an average dusting potential ranging from 50 - 371 mg/m3. The solid formulations XT 5 P and XT 25 exhibited a lower dusting potential of 0 to 3 mg/m3.
Carrier
Solid form: wheat flour and sunflower oil (the formulation XT P is without sunflower oil)
Liquid form: sorbitol, sodium benzoate, sodium citrate dehydrate and water
Handling
The European Commission states: "For users of the additive and premixtures, feed business operators shall establish operational procedures and organisational measures to address potential risks resulting from their use. Where those risks cannot be eliminated by such procedures and measures, the additive and premixtures shall be used with personal protective equipment, including breathing, skin and eye protection for solid forms, and breathing protection for liquid forms."
Manufacturer
AB Vista
List of references
EFSA (2008). Safety and efficacy of Econase XT P/L as feed additive for chickens for fattening, chickens reared for laying, turkeys for fattening, turkeys reared for breeding and piglets (weaned). The EFSA Journal (2008) 712, 1-19
EFSA (2011). Scientific Opinion on the safety and efficacy of Econase XT P/L (endo-1,4-beta-xylanase) as a feed additive for laying hens, minor poultry species (including ducks, geese, quails, pheasants and pigeons) and pigs for fattening. EFSA Journal 2011; 9(6):2277
EFSA (2021). Safety and efficacy of a feed additive consisting of endo-1,4-b-xylanase (ECONASE® XT) produced by Trichoderma reesei CBS 140027 as a feed additive for piglets (weaned), pigs for fattening, chickens for fattening, chickens reared for laying, laying hens, turkeys for fattening, turkeys reared for breeding and minor poultry species (Roal Oy). EFSA Journal 2021;19(4):6536
EU (2009). Commission Regulation (EC) No 902/2009 of 28 September 2009 concerning the authorisation of an enzyme preparation of endo-1,4-beta-xylanase produced by Trichoderma reesei (CBS 114044) as a feed additive for weaned piglets, chickens for fattening, chickens reared for laying, turkeys for fattening and turkeys reared for breeding (holder of authorisation Roal OY). Official Journal of the European Union. L256/23
EU (2011). Commission implementing Regulation (EC) No 1110/2011 of 3 November 2011 concerning the authorisation of an enzyme preparation of endo-1,4-beta-xylanase produced by Trichoderma reesei (CBS 114044) as a feed additive for laying hens, minor poultry species and pigs for fattening (holder of authorisation Roal OY). Official Journal of the European Union. L287/27
EU (2018). Commission implementing Regulation (EU) No 2018/1569 of 18 October 2018 amending implementing Regulation (EU) No 1110/2011 concerning the authorisation of an enzyme preparation of endo-1,4-beta-xylanase produced by Trichoderma reesei (CBS 114044) as a feed additive for laying hens, minor poultry species and pigs for fattening (holder of authorisation Roal Oy). Official Journal of the European Union. L 262/37-39
EU (2023). COMMISSION IMPLEMENTING REGULATION (EU) 2023/1332 of 29 June 2023 concerning the renewal of the authorisation of a preparation of endo-1,4-beta-xylanase produced by Trichoderma reesei CBS 114044 as a feed additive for chickens for fattening, chickens reared for laying, turkeys for fattening, turkeys reared for breeding and weaned piglets (holder of the authorisation: Roal Oy), and repealing Regulation (EC) No 902/2009. Official Journal of the European Union L166/102-105