Introduction
Lavipan® is a probiotic product containing four different lactobacillus strains and yeast. The EU has authorised its use in chickens for fattening. Lavipan® is available in two different concentrations.
Manufacturer´s main claims
Improves weight gain significantly.
Quicker recovery after antibiotic treatment.
Improves feed conversion
Technical specifications of Lavipan®
EU category
Zootechnical additive
Functional group of additives
Gut flora stabiliser
Active substance
Lactococcus lactis (PCM B/00039)
Carnobacterium divergens (PCM KKP 2012p)
Lactobacillus casei (PCM B/00080)
Lactobacillus plantarum (PCM B/00081)
Saccharomyces cerevisiae (PCM KKP 2059p)
Activity in the product
Minimum content:
Lactococcus lacti: ≥5 x 108 CFU/g
Carnobacterium divergens: ≥ 3 x 108 CFU/g
Lactobacillus casei: ≥1 x 108 CFU/g
Lactobacillus plantarum: ≥3 x 108 CFU/g
Saccharomyces cerevisiae: ≥1 x 107 CFU/g
EU approval, minimum content
No maximum inclusion for the animal categories below
Chickens for fattening, minimum content:
(LAB), 5 x 108 CFU/kg feed
Yeast, 5 x 106 CFU/kg feed
End of period of authorisation
Chickens for fattening: 6 July 2027
EU code
4b1892
Product storage stability
Twelve samples from one batch were stored for 12 months at either 4°C 35% RH or 20°C 50% RH. After 12 months, lactobacilli activity was reduced by 0.5 log units when stored at 20°C. The yeast concentration was decreased by 1 log unit after only one month of storage time at 20°C.
Storage stability in feed premix
The product manufacturer does not recommend including the product in vitamin/mineral premixes.
Three batches of turkey mash feed were supplemented with the product and stored at either 4°C 50% RH or 20°C 35% RH. After one month of storage at 20°C, a loss of 0.5 log unit of the lactobacilli was observed. After three months, the loss exceeded one log unit loss. A reduction of 0.5 log units of the yeast cell count was observed after eight weeks of storage at 4°C and after two weeks when stored at 20°C. After three months, the yeast cell count was reduced by 2 log units.
Heat stability
An undescribed mash feed was pelleted at 60, 70, or 80°C. Both lactobacilli and yeast lost less than 0.5 log units.
Homogeneity
The coefficient of variation (CV) was investigated when supplemented to three batches of an unspecified feed. The CV was less than 15% for the cell counts.
Compatibility claims
Compatible with diclazuril, salinomycin sodium, decoquinate, maduramicin and narasin+nicarbazin
Handling
Inhalation of dust should be avoided. Gloves and goggles should be worn to reduce contact with dust.
Producer
JHJ
List of references of references
EFSA (2016). Safety and efficacy of Lavipan® (Lactococcus lactis B/00039, Carnobacterium divergens KKP 2012p, Lactobacillus casei B/00080, Lactobacillus plantarum B/00081 and Saccharomyces cerevisiae KKP 2059p) for weaned piglets, chickens for fattening and turkeys for fattening. EFSA Journal 2016;14(9):4555
EU (2017). Commission Implementing Regulation (EU) 2017/1008 of 15 June 2017 concerning the authorisation of the preparation of of Lactococcus lactis PCM B/00039, Carnobacterium divergens PCM KKP 2012p, Lactobacillus casei PCM B/00080, Lactobacillus plantarum PCM B/00081 and Saccharomyces cerevisiae PCM KKP 2059p as a feed additive for chickens for fattening (holder of authorisation JHJ Ltd). Official Journal of the European Union. L153/16-18