Avemix XG 10
Avemix® XG 10 contains both beta-xylanase and beta-glucanase activity. The product is authorised for use in the EU in piglets and pigs for fattening. It is also authorised for use in chickens for fattening and other avian species.
Avemix® XG 10 is available both in dry and liquid forms.
Manufacturer´s main claims
Improves animal performance due to higher digestibility of the feed
Enables high inclusion of by-products
Table 1. Technical specifications Avemix® XG 10 (solid)
| EU category | Zoo-technical additive |
| Functional group of additives | Digestibility enhancer |
| Active substance IUB No. |
endo-1,4-beta-xylanase (EC 3.2.1.8) and endo-1,3(4)-beta-glucanase (EC. 3.2.1.6) |
| Enzymatic activity in the product | 40,000 XU/g 9,000 BGU/g |
| EU approval | Piglets (weaned): 4000 XU/kg feed and 900 BGU/kg feed Pigs for fattening: 4000 XU/kg feed and 900 BGU/kg feed Chickens for fattening: 3000 XU/kg feed and 675 BGU/kg feed Laying hens and minor poultry species for laying: 4000 XU/kg feed and 900 BGU/kg feed Minor poultry species for fattening: 3000 XU/kg feed and 675 BGU/kg feed Turkeys for fattening: 4000 XU/kg feed and 900 BGU/kg feed |
| End of period of EU authorisation | Piglets (weaned): 17 November 2021* Pigs for fattening: 14 November 2023* Minor porcine species for fattening other Sus scrofa domesticus: 14 November 2023* Chickens for fattening: 17 March 2031 Laying hens and minor poultry species for laying: 15 November 2022* Minor poultry species for fattening: 15 November 2022* Turkeys for fattening: 14 November 2023* *: An application in accordance with Article 7 has been submitted |
| EU code | 4a9 |
| Recommended dosage | 100 g/ton feed |
| Derived from micro-organism | Xylanase derived from Trichoderma reesei (MUCL 49755) and beta-glucanase derived from Trichoderma reesei (MUCL 49754) |
| Product storage stability | When stored at 25°C, no loss of enzymatic was observed after six months. After 13 months, the enzymatic activity was reduced to 89% beta-glucanase and 81% xylanase. |
| Storage stability in feed and premix | The xylanase and glucanase activities were 107 and 83 % when the feed was stored for three months at 25°C. When added to a premix, the xylanase and glucanase activities were 110 and 99 %, respectively, when the premix was stored at 25°C for three months. |
| Heat stability | One batch of AveMix XG 10 was tested in a pelleting trial. At a pelleting temperature of 75°C, the activity of xylanase was 79 %, and the activity of glucanase was 84 %. |
| Package size | 25 kg PE-inliner bag |
| Handling | The product should be regarded as a skin and respiratory sensitiser. |
| Carrier | Soybean meal |
| Producer | Aveve |
Table 2. Avemix® XG 10 (Liquid)
| EU category | Zoo-technical additive |
| Functional group of additives | Digestibility enhancer |
| Active substance IUB No. |
endo-1,4-beta-xylanase (EC 3.2.1.8) and endo-1,3(4)-beta-glucanase (EC. 3.2.1.6) |
| Enzymatic activity in the product | 40,000 XU/g 9,000 BGU/g |
| EU approval | Piglets (weaned): 4000 XU/kg feed and 900 BGU/kg feed Pigs for fattening: 4000 XU/kg feed and 900 BGU/kg feed Chickens for fattening: 3000 XU/kg feed and 675 BGU/kg feed Laying hens and minor poultry species for laying: 4000 XU/kg feed and 900 BGU/kg feed Minor poultry species for fattening: 3000 XU/kg feed and 675 BGU/kg feed Turkeys for fattening: 4000 XU/kg feed and 900 BGU/kg feed |
| End of period of EU authorisation | Piglets (weaned):17 November 2021* Pigs for fattening: 14 November 2023* Minor porcine species for fattening other Sus scrofa domesticus: 14 November 2023* Chickens for fattening: 17 March 2031 Laying hens and minor poultry species for laying: 15 November 2022* Minor poultry species for fattening: 15 November 2022* Turkeys for fattening: 14 November 2023* *: An application in accordance with Article 7 has been submitted |
| EU code | 4a9 |
| Recommended dosage | 100 g/ton feed |
| Derived from microorganism | Xylanase derived from Trichoderma reesei (MUCL 49755) and beta-glucanase derived from Trichoderma reesei (MUCL 49754) |
| Product storage stability | When stored at 25°C no loss of enzymatic was observed. After 13 months, the enzymatic activity was reduced to 89% beta-glucanase and 81% xylanase. |
| Heat stability | Not available |
| Package size | 1000 litre IBC container |
| Handling | The product should be regarded as a skin and respiratory sensitiser. |
| Carrier | Water and sorbitol |
| Producer | Aveve |
List of references
EFSA (2009). Safety and efficacy of AveMix XG 10 (endo-1,4-beta-xylanase and endo-1,3(4)-beta-glucanase) for use as feed additive for chickens for fattening. The EFSA Journal (2009) 1094, 1-17
EFSA (2013). Scientific Opinion on the safety and efficacy of AveMix XG 10 (endo-1,4-beta-xylanase and endo-1,3(4)-beta-glucanase) as a feed additive for pigs and minor porcine species. EFSA Journal 2013; 11(4):3171
EU (2011). Commission Regulation (EU) No 335/2011 of 7 April 2011 amending Regulation (EC) No 1091/2009 as regards the minimum content of the enzyme preparation of endo-1,4-beta-xylanase produced by Trichoderma reesei (MUCL 49755) and endo-1,3(4)-beta-glucanase produced by Trichoderma reesei (MUCL 49754) as a feed additive for chickens for fattening. Official Journal of the European Union. L 94/14-16
EU (2011). Commission Implementing Regulation (EU) No 1088/2011 of 27 October 2011 concerning the authorisation of an enzyme preparation of endo-1,4-beta-xylanase produced by Trichoderma reesei (MUCL 49755) and endo-1,3(4)-beta-glucanase produced by Trichoderma reesei (MUCL 49754) as a feed additive for weaned piglets (holder of authorisation Aveve NV). Official Journal of the European Union. L281/14-15
EU (2012). Commission Implementing Regulation (EU) No 989/2012 of 25 October 2012 concerning the authorisation of endo-1,4-beta-xylanase produced by Trichoderma reesei (MUCL 49755) and endo-1,3(4)-beta-glucanase produced by Trichoderma reesei (MUCL 49754) as a feed additive for laying hens and minor poultry species for fattening and laying (holder of authorisation Aveve NV). Official Journal of the European Union. L 297/11-14
EU (2013). Commission Implementing Regulation (EU) No 1040/2013 of 24 October 2013 concerning the authorisation of a preparation of endo-1,4-beta-xylanase produced by Trichoderma reesei (MUCL 49755) and endo-1,3(4)-beta-glucanase produced by Trichoderma reesei (MUCL 49754) as a feed additive for pigs for fattening and minor porcine species for fattening other than Sus scrofa domesticus and turkeys for fattening (holder of authorisation Aveve NV). Official Journal of the European Union. L 283/46-49
EU (2021). Commission Implementing Regulation (EU) 2021/329 of 24 February 2021 concerning the renewal of the authorisation of a preparation of endo-1,4-beta-xylanase and endo-1,3(4)-beta-glucanase for chickens for fattening (holder of authorisation AVEVE NV) and repealing Regulation (EC) No 1091/2009. Official Journal of the European Union. L65/38-42