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Phyzyme® contains 6-phytase. The product is authorised for use in the EU in piglets, pigs for fattening, sows and various other species. Phyzyme® is available both in dry and liquid forms.

Phyzyme® products:

Phyzyme® XP 5000G (granulate) and Phyzyme XP 5000L (liquid)

Manufacturer´s main claims
Lowers the feed costs
Improves the environment

Table 1. Technical specifications Phyzyme® XP 5000G and Phyzyme® XP 5000L

EU category Zoo-technical additives
Functional group of additives Digestibility enhancer
Active substance 6-Phytase (EC 3.1.3.26)
Phytase activity in the product 5000 FTU/g
EU approval, minimum content No maximum content for any of the animal categories below
Piglets (weaned): 250 FTU/kg feed
Pigs for fattening: 250 FTU/kg feed
Sows: 500 FTU/kg feed
Chickens for fattening: 250 FTU/kg feed 
Turkeys for fattening: 250 FTU/kg feed 
Laying hens: 150 FTU/kg feed
Ducks for fattening: 250 FTU/kg feed 
All avian species for fattening other than chickens, turkeys and ducks for fattening: 250 FTU/kg feed
All avian species reared for laying other than laying hens: 150 FTU/kg feed
End of period of EU authorisation All species above except all avian species except chickens, turkeys and ducks: 26 February 2030
All avian species for fattening other chickens, turkeys and ducks: 9 October 2022
All avian species reared for laying other than laying hens: 9 October 2022
EU code 4a1640
Production organism Genetically modified Schizosaccharomyces pombe, ATCC 5233
Donor organims Escherichia coli
Product storage stability XP 5000G: 12 months when stored in original packaging at 20°C; XP 5000L: 9 months when stored in original packaging at 20°C
Storage stability in feed XP 5000G remains stable for at least three months when mixed into feed or premixes and stored at 20°C. XP 5000L remains stable for at least three months when mixed into feed.
Heat stability Rasmussen (2010) showed that Phyzyme XP is heat stable at high pelleting temperatures. A pelleting temperature at 95°C reduced the phytase activity by 13 %. It is advised to apply XP 5000L only post-pelleting
Carrier L: Water, Sorbitol, Sodium chloride, Sodium citrate, Sodium benzoate, Potassium sorbate
P: Fermentation liquor, Sodium sulphate, Hydrated magnesium silicate, Starch, Polyvinyl alcohol
Package size XP 5000G : 25 kg bags or 1000 kg big bagsXP 5000L : 200 or 1000 kg containers
Handling May cause sensitisation by inhalation. Avoid contact with skin. Wear suitable protective clothing and gloves
Producer Danisco Animal Nutrition (DuPont)

List of references


EFSA (2008). Safety an efficacy of Phyzyme XP 10000 (TPT/L), 6-phytase, as a feed additve for chickens for fattening, laying hens, ducks for fattening, turkeys for fattening, piglets (weaned), pigs for fattening and sows. The EFSA Journal (2008) 915, 1-10

EU (2009). Commission Regulation (EC) No 379/2009 of 8 May 2009 concerning the authorisation of a new use of 6-phytase EC 3.1.3.26 as a feed additive for chickens for fattening, turkeys for fattening, laying hens, ducks for fattening, piglets (weaned), pigs for fattening and sows (holder of authorisation Danisco Animal Nutrition, legal entity Danisco (UK) Limited). Official Journal of the European Union, L 116/6

EU (2012). Commission Regulation (EU) No 840/2012 of 18 September 2012 concerning the authorisation of 6-phytase (EC 3.1.3.26) produced by Schizosaccharomyces pombe (ATCC 5233) as a feed additive for all avian species for fattening other than chickens for fattening, turkeys for fattening, and ducks for fattening and all avian species for laying other than laying hens (holder of the authorisation Danisco Animal Nutrition). L252/14-16

EU (2020). Commission implementing Regulation (EU) No 2020/166 of 5 February 2020 concerning the renewal of the authorisation of 6-phytase produced by Schizosaccharomyces pombe (ATCC 5233) as a feed additive for chickens for fattening, laying hens, turkeys for fattening, ducks for fattening, weaned piglets, pigs for fattening and sows repealing Regulation (EC) No 785/2007 (holder of authorisation Danisco (UK) Ltd, trading as Danisco Animal Nutrition represented by Genencor B.V.). Official Journal of the European Union, L34/43-45 

Rasmussen, D. K. (2010). Forskel i varmestabilitet for fytase og xylanaseprodukter i foder. Videncenter for Svineproduktion. Meddelelse nr. 875

 

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