Bonvital

Bonvital contains Enterococcus faecium and is authorised in the EU for use in piglets, pigs for fattening, sows, chickens for fattening, chickens reared for laying and minor poultry species other than those used for laying. The product is available both as a powder and as a microencapsulated additive.

Manufacturer´s main claims
Increase daily weight gain
Improves feed conversion
Improves general health condition
Decreases rate of mortality

Bonvital is available both as powder and granulate

Technical specifications Bonvital

EU category	Zoo-technical additive
Functional group of additives	Gut flora stabiliser
Active substance	Enterococcus faecium (DSM 7134)
Activity in the product	1 x 10¹⁰ CFU/g product
EU approval	Piglets:0.5 x 10⁹ - 4 x 10⁹ CFU/kg feed Pigs for fattening: 0.2 x 10⁹ - 1 x 10⁹ CFU/kg feed Sows: 0.5 x 10⁹ CFU/kg feed or 2.5 x 10⁸ CFU/l drinking water Chickens for fattening: 5 x 10⁸ CFU/kg feed Chickens reared for laying: 5 x 10⁸ CFU/kg feed Minor poultry species (other than those used for laying): 5 x 10⁸ CFU/kg feed
End of period of authorisation	Piglets and pigs for fattening: 26 February 2030 Sows, for application in feed: 5 November 2024 Sows, for application in drinking water: 25 August 2029 Chickens for fattening: 26 November 2020 (An application in accordance with Article 7 has been submitted to EFSA) Chickens reared for laying: 2 September 2023 Minor poultry species (other than those used for laying: 2 September 2023
EU code	4b1841
Recommended dosage	Piglets and sows: 0.5 kg/t feed Pigs for fattening: 0.2 kg/t feed
Product storage stability	Storage stability of the product in its original packaging was tested at 4°C, 20°C and 37°C. The test showed that the product is stable for 12 months when stored at 4°C or 20°C. At 37°C it is stable for 6 months.
Storage stability in feed and premix	Both the powder and granulate form of the product was added to mineral/vitamin premix and stored for six months at 20°C under dry conditions. After six months there was no significant loss of viability. The product was added either as the powder or the granulate form to piglet feed and stored for four months at 20°C. The results support that both product forms are stable in feed when stored for four months.
Heat stability	The granulated form of the product was added to feed for piglets and pelleted at 70-72°C. After pelleting, 85% of the initial activity was recovered
Carrier	Powder: Whey powder; Granulates: saccharose, maltodextrin
Handling	The product should be considered as a potential skin and eye irritant and sensitiser
Producer	Lactosan

List of references

EFSA (2013). Scientific Opinion on the safety and efficacy of Bonvital (Enterococcus faecium) for chickens reared for laying and minor avian species. EFSA Journal 2013; 11(4):3167

EU (2007). Commission Regulation (EC) No 538/2007 of 15 May 2007 concerning the authorisation of a new use of Enterococcus faecium DSM 7134 (Bonvital) as a feed additive. Official Journal of the European Union. L 128/16

EU (2007). Commission Regulation (EC) No 1521/2007 of 19 December 2007 concerning the authorisation of a new use of Enterococcus faecium DSM 7134 (Bonvital) as a feed additive. Official Journal of the European Union L 335/24

EU (2010). Commission Regulation (EU) No 998/2010 of 5 November 2010 concerning the authorisation of Enterococcus faecium DSM 7134 as a feed additive for chickens for fattening (holder of the authorisation Lactosan GmbH & Co KG). Official Journal of the European Union. L 290/22-23

EU (2013). Commission Regulation (EU) No 775/2013 of 12 August 2013 concerning the authorisation of a preparation of Enterococcus faecium DSM 7134 as a feed additive for chickens reared for laying and minor poultry species other than those used for laying (holder of the authorisation Lactosan GmbH & Co Kg). Official Journal of the European Union.

EU (2014). Commission Regulation (EU) No 1083/2014 of 15 October 2014 concerning the authorisation of a preparation of Enterococcus faecium DSM 7134 (Bonvital) as a feed additive for sows. L298/5

EU (2019). Register of feed additives pursuant to Regulation (EC) No 1831/2003. Annex I: List of additives. Edition 11/2019 (277).

EU (2019). Commission implementing Regulation (EU) 2019/1315 of 2 August 2019 concerning the authorisation of a preparation of Enterococcus faecium DSM 7134 as a feed additive (in water for drinking) for sows (holder of authorisation Lactosan GmbH & Co). Official Journal of the European Union L205/7-9

EU (2020). Commission implementing Regulation (EU) 2020/159 of 5 February 2020 concerning the renewal of the authorisation of Enterococcus faecium DSM 7134 as a feed additive for weaned piglets and pigs for fattening and repealing Regulation (EC) No 538/2007 (holder of authorisation Lactosan Starterkulturen GmbH & Co). Official Journal of the European Union L34/22-24