B-Act® is a probiotic product containing Bacillus licheniformis. The product is authorised in the EU for use in poultry. Lavipan® is available in two different concentrations.

Manufacturer´s main claims

Improves technical performance
Mitigates bacterial enteric challenges such as dysbacteriosis and necrotic enteritis
Stable throughout production, storage and digestion

Technical specifications B-act®

EU category Zootechnical additives
Functional group of additives Gut flora stabilisers
Active substance Bacillus licheniformis, DSM 28710
Activity in the product Minimum content:
3.2 x 10
9 CFU/g
EU approval All species:
1.6 x 109 CFU/kg feed
End of period of authorisation Chickens for fattening: 8 November 2027
Chickens reared for laying: 8 November 2027
Turkeys for fattening: 25 June 2029
Turkeys reared for breeding: 25 June 2029
Minor poultry species for fattening or reared for breeding: 25 June 2029
EU code 4b1828
Product storage stability Three batches of the product were stored for two years at either 25°C or 40°C. Bacillus licheniformis counts after two years at 25°C were within specifications with a minor loss of activity. When stored at 40°C  the activity went from 3.2 x 109 CFU/g to 2.5-2.8 x 109 CFU/g
Storage stability in feed and premix The product was added to a vitamin/mineral premix and stored for 6 months at either 25°C/RH 60% or 40°C/RH 75%. At the end of the storage period, the loss of Bacillus licheniformis activity was less than 0.1 log values at both conditions.
The product was also supplemented to a mash feed and stored for 3 months at 25°C/RH 60% or for 4 weeks at 40°C/RH 75%. After 3 months at 25°C, the loss of viable cells was below 0.5 log values. When stored at 40°C the loss exceeded 0.5 log values.
Heat stability The product was added to a poultry feed and pelleted at 85°C.  There was essentially no loss of activity after pelleting at 85°C. Samples of pelleted feed were furthermore stored for up to 3 months at either 25°C or 40°C.  A loss of 0.3-0.4 log values was observed after 3 months at 25°C. At 40°C, there was a loss of 0.5 log values after 4 weeks.
Homogeneity Samples of the feed used for stability tests were collected. The analytical results showed a CV of 8% when the product was added to vitamin/mineral premixes and mash feed. When added to pelleted feed the CV was 10%.
Particle size All particles are below 500 μm and 30% are below 100 μm. The mean value of the dusting potential is 2.73 g/m3. In the dust fraction the mean value was 2 μm.
Compatibility claims The product is compatible with: Decoquinate, diclazuril, halofuginone, nicarbazin, robenidine hydrochloride, lasalocid A sodium, maduramicin ammonium, monensin sodium, narasin or salinomycin sodium.
Handling Inhalation of dust should be avoided. Gloves and goggles should be worn to reduce contact with dust
Producer Huvepharma


List of references

EFSA (2016).  Safety and efficacy of B-Act® (Bacillus licheniformis DSM 28710) for chickens for fattening and chickens reared for laying. EFSA Journal, 2016;14(11):4615

EU (2017). Commission implementing Regulation (EU) 2017/1904 of 18 October 2017 concerning the authorisation of a preparation Bacillus licheniformis DSM 28710 as a feed additive for chickens for fattening and chickens reared for laying (holder of authorisation Huvepharma NV). Official Journal of the European Union. L 269/27-29

EU (2019). Commission implementing Regulation (EU) 2019/914 of 29 May 2019 concerning the authorisation of a preparation of Bacillus licheniformis DSM 28710 as a feed additive for turkeys for fattening, turkeys reared for breeding and minor poultry species for fattening and reared for breeding (holder of authorisation Huvepharma NV). Official Journal of the European Union. L 146/60-62