Introduction
The main enzymatic activity in Hostazym X® is xylanase. The product is authorised for use in the EU in piglets, pigs for fattening, chickens for fattening, laying hens, turkeys for fattening and minor poultry species for laying and for fattening.
Hostazym X® is available in both dry and liquid formulations.
Technical specifications of Hostazym X® (Dry and Liquid)
EU category
Zootechnical additives
Functional group of additives
Digestibility enhancers
Active substance
endo-1,4-beta-xylanase (EC 3.2.1.8)
Enzymatic activity in the product
Xylanase: 6,000 EPU/g
EU approval, minimum content
1500 EPU/kg feed
Suckling piglets
Weaned piglets
Pigs for fattening
Minor porcine species for fattening
Chickens for fattening
Chickens reared for laying
All poultry species for breeding
Laying hens
Minor poultry species for laying
Minor poultry species reared for laying
1050 EPU/kg feed
Turkeys for fattening
Turkeys reared for breeding
Minor poultry species for fattening
Carp
End of period of EU authorisation
26 March 2034
EU code
4a1617
Production organism
Trichoderma citrinoviride Bisset (IM SD 135)
Product storage stability
Solid product: After 24 months of storage in the bag at 25°C, the remaining xylanase activity was above 90 %. When stored for six months at 40°C the recovery rate of xylanase was 79%
Liquid product: After 12 months of storage in a plastic bottle at 25°C, the remaining xylanase activity was above 88 %. When stored for six months at 40°C the recovery rate of xylanase was above 79%
Storage stability in premix and feed
A premixture containing the solid Hostazym X was stored for six months at either 25°C or 35°C. The mean rate of recovery was 93% and 80% at 25°C and 35°C, respectively. Pelleted feed supplemented with solid Hostazym X was stored for three months at either 25°C or 35°C. The mean rate of recovery was above 90% and above 80% at 25°C and 35°C, respectively.
Pelleted feed supplemented with liquid Hostazym X was stored for three months at either 25°C or 35°C. The mean rate of recovery was above 90% and above 83% at 25°C and 35°C, respectively.
Heat stability
When pelleting at temperatures between 65 and 75°C, more than 90 % of the initial xylanase activity was recovered.
Homogeneity
Subsamples of mash or pelleted feed supplemented with the product (solid or liquid) were collected and analysed. The CV ranged from 7.0 to 14.3% with the solid product and 5.8 to 11.4 with the liquid.
Physical properties
The Particle size distribution was studied, and it was found that around 98% of the particles are bigger than 100 μm.
A dusting potential test showed that both formulations´ dusting potential is 0 g per m3.
Carrier
Solid product: Wheat meal and pre-gelatinized starch
Liquid product: Sorbitol, propylene glycol, sodium benzoate, potassium sorbate and water
Package size
25 kg multi-layer paper bags
200 ltr plastic drums or 1000 ltr IBC container
Handling
The European Commission states: "For safety: breathing protection, glasses and gloves shall be used during handling."
Manufacturer
Huvepharma
List of references
EFSA (2013). Scientific Opinion on the Safety and Efficacy of Hostazym X (endo-1,4-beta-xylanase) as a feed additive for poultry, piglets and pigs for fattening. EFSA Journal 2013;11(2):3105
EU (2024). COMMISSION IMPLEMENTING REGULATION (EU) 2024/780 of 5 March 2024 concerning the renewal of the authorisation of a preparation of endo– 1,4-beta-xylanase produced by Trichoderma citrinoviride DSM 34663 as a feed additive for all poultry species for fattening, all poultry species for laying and reared for laying, weaned piglets, pigs for fattening and carp, the authorisation of that preparation as a feed additive for all poultry species for breeding, turkeys reared for breeding, minor poultry species reared for breeding, ornamental birds, suckling piglets and minor porcine species for fattening (holder of authorisation: Huvepharma NV) and repealing Implementing Regulations (EU) 2015/1043, (EU) 2017/1906 and (EU) 2018/327